Projects

Break Through Cancer empowers outstanding researchers and physicians to both intercept and find cures for the deadliest cancers by stimulating radical collaboration.

BTC Central Website

Independent Projects / Publications associated with Matthew D. Shoulders Lab at MIT

ABSTRACT – OVERALL The primary focus of the MIT/DFCI Center for Systems Biology of Glioblastoma is to understand the intersections between neurons, immune cells, and tumor cells in this deadly tumor. The lack of response to immunotherapy strategies despite prominent infiltrates of immune cells in many GBM highlights the immuno- suppressive nature of the GBM microenvironment and the importance of more clearly understanding the dynamic interactions at the tumor/immune interface. Similarly, interactions ...